La
berberina es un alcaloide extraído de diversas plantas que se utilizan en la
medicina tradicional china. En este compuesto tenemos un ejemplo de lo que a
veces puede suponer una diferencia entre lo científico y lo oficial debido, en
gran parte a los intereses comerciales.
La
berberina tiene efectos anti-inflamatorios y anti-diabéticos, puede mejorar la
salud intestinal (microbiota) y reducir el colesterol total. Las
investigaciones en humanos y animales demuestran que 1500 mg de berberina,
tomada en tres dosis de 500 mg cada una, equivalen a tomar 1.500 mg de
metformina o a 4 mg de glibenclamida, los dos productos farmacéuticos para el
tratamiento de la diabetes tipo II.
El
mecanismo responsable de la acción de la berberina es el mismo que el del fármaco
Metformina, su capacidad para activar una enzima llamada quinasa del AMP
(AMPk), inhibiendo, a su vez, la proteína-tirosina fosfatasa 1B (PTP1B) (un
regulador negativo de la vía de señalización de la insulina).
La
dosis estándar es de 900-2.000 mg al día dividida en tres dosis (se debe tomar
con una comida, o poco después, para aprovechar el aumento de la glucemia y
lípidos asociada con la alimentación). Si se asocia a propóleo (producto de las
abejas), su eficacia aumenta.
Pues
bien, con todos esos efectos idénticos a la Metformina ¿Por qué no es una
alternativa en la fitoterapia a este medicamento en el tratamiento de la
diabetes 2?
Habría
que preguntar a los responsables, por qué en Holanda se vende libremente en el
mercado de los productos herbarios (Enlace)
y en España no.
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